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Health Policy

Elsevier BV

Preprints posted in the last 90 days, ranked by how well they match Health Policy's content profile, based on 11 papers previously published here. The average preprint has a 0.02% match score for this journal, so anything above that is already an above-average fit.

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Waiting time for scheduled outpatient specialist consultations by access pathway in public hospitals in Ecuador

Armijos Briones, M.; Diaz Cercado, E.; Marcillo-Toala, O.; Ayala Aguirre, P. E.; Benitez Sellan, P. L.; Lanata-Flores, A.; Armijos Bazurto, N.

2026-05-06 health policy 10.64898/2026.05.04.26352408 medRxiv
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ObjectiveTo quantify waiting time in days for scheduled outpatient specialist consultations and to compare waiting time between standardized and non-standardized access pathways in Ecuadorian public hospitals. MethodsWe analyzed hospital-based survey data from Ecuadorian public hospitals, restricted to adults attending a scheduled outpatient specialist consultation (n = 4,436). Emergency care, unscheduled urgent visits, procedures, and follow-up visits were excluded by design. Access pathway was classified from participants self-report as standardized (institutional or system-based) or non-standardized (informal or non-system-based). Waiting time, defined as the number of days between obtaining the appointment and attending the consultation, was compared using the Mann-Whitney U test. Sociodemographic correlates of non-standardized access were examined using adjusted logistic regression, and adjusted median differences were estimated using quantile regression ({tau} = 0.50). Analyses were stratified into direct-access specialties and referral-required specialties. ResultsNon-standardized access was associated with shorter waiting times than standardized access. In adjusted median regression, non-standardized access was associated with a 3.2-day shorter median waiting time (95% CI -4.6 to -1.8). The difference was larger in direct-access specialties (-15.0 days, 95% CI -15.0 to -6.0) than in referral-required specialties (-5.0 days, 95% CI -5.0 to 0.0). ConclusionAmong patients who attended a scheduled outpatient specialist consultation in Ecuadorian public hospitals, non-standardized access was associated with shorter waiting times, particularly in direct-access specialties. These findings suggest that, within routine outpatient care, parallel access pathways may shape timeliness and warrant greater transparency in appointment allocation and referral coordination.

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Variation in Hospital Visiting Hour Policies in US Acute Care Facilities: An Exploratory Cross-Sectional Analysis

Garcia, C. Y.; Chou, C. Y.; Caso, E.; Hudspeth, J. C.; Allan-Blitz, L.-T.

2026-04-28 health policy 10.64898/2026.04.27.26351861 medRxiv
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BackgroundHospital visiting-hour policies vary widely across the United States, yet the structural factors shaping this variation remain poorly characterized. ObjectiveThis study investigates how hospital-level financial characteristics, payer mix, and rurality relate to the restrictiveness of inpatient visiting-hour policies, and assesses whether these relationships differ across states with diverse Medicaid expansion statuses. DesignCross-sectional observational analysis of hospital visitor policies in four states (Massachusetts, Wisconsin, Tennessee, and South Carolina) selected based on Medicaid expansion status, population size, and hospital density. ParticipantsA total of 318 acute-care hospitals were included using publicly available data from the Centers for Medicare & Medicaid Services and the National Academy for State Health Policy. Main MeasuresThe primary outcome was total daily visiting hours in general inpatient wards. Predictors included volume/capacity, patient mix, financial performance/efficiency, geography and organizational structure. Key ResultsHospital-level characteristics including higher Medicaid payer mix, stronger financial margins, greater inpatient occupancy, and larger size were associated with shorter visiting hours in unadjusted analyses. Commercial payer mix and rurality predicted longer hours. Mean visiting duration was 14.1 hours/day (SD = 5.07; range 0-24), with Massachusetts having the shortest on average across states (10.5 hours/day) and Wisconsin the longest (16.3 hours/day). Medicaid payer mix was the only predictor associated with visiting-hour restrictiveness after multiple-testing correction. Each 10-percentage-point increase in Medicaid payer mix was associated with an approximately 11.3% decrease (p = 0.002) in visiting hours. Within-state variation exceeded the differences between-states. ConclusionsVisitation hours vary considerably, with correlations around rurality of the community served, size of the hospital, and the number of patients on Medicaid. Medicaid payer mix emerged as the most consistent predictor of restrictiveness after adjustment. Hospitals can use these findings to evaluate visitation practices to balance patient-centered care with operational demands.

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Willingness to pay for improved long-term care insurance among beneficiaries or primary family caregivers in a Chinese pilot city: A contingent valuation study

Cao, H.; Li, X.; Cao, Z.

2026-06-01 health economics 10.64898/2026.05.28.26354309 medRxiv
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Background Chinas rapidly ageing population has increased the demand for long-term care insurance (LTCI), while the sustainability of current financing arrangements remains uncertain. Understanding willingness to pay (WTP) for improved LTCI services among LTCI beneficiaries or primary family caregivers may provide empirical evidence for discussions on acceptable and sustainable contribution mechanisms. Methods We conducted a contingent valuation survey among 278 LTCI beneficiaries or primary family caregivers in Panjin City, Liaoning Province, China. An iterative bidding game with randomized starting bids was used to elicit monthly WTP for a predefined LTCI service improvement scenario. Tobit regression models with heteroskedasticity-robust standard errors were used to estimate factors associated with WTP, including household income, disability severity, satisfaction with current services, and demographic characteristics. Results The mean monthly WTP for improved LTCI services was approximately CNY 300, compared with the current average monthly premium of approximately CNY 120. The median WTP was CNY 250. Higher household income was positively associated with WTP. Compared with participants with monthly household income below CNY 5,000, those in the highest income group above CNY 30,000 reported an additional WTP of CNY 178.9. More severe disability was also associated with higher WTP, whereas greater satisfaction with current LTCI services was associated with lower WTP. These associations were generally consistent across alternative model specifications. Conclusions LTCI beneficiaries or primary family caregivers in this Chinese pilot city reported a willingness to contribute more for improved LTCI services, particularly among those with higher income, greater care needs, or lower satisfaction with current services. These findings may inform discussions on differentiated contribution arrangements and service quality improvements in LTCI financing reform. However, the results should be interpreted cautiously because the study was conducted in a single pilot city and relied on stated-preference data.

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The Evolution and Equity of Chinas Pharmacist Workforce in Healthcare Institutions: A Provincial Panel Data Analysis, 2007-2023 Evolution and equity of China's pharmacist workforce

xia, y.; Sun, L.; Zhao, Y.

2026-04-23 health policy 10.64898/2026.04.22.26351514 medRxiv
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BackgroundChina has implemented policies to strengthen its pharmacist workforce since the 2009 healthcare reform, yet a comprehensive evaluation of their long-term systemic effects is lacking. ObjectiveTo systematically analyze the evolution of Chinas pharmacist workforce in healthcare institutions from 2007 to 2023 across four dimensions: quantity, quality, structure, and distribution, providing an empirical foundation for policy optimization. MethodsA retrospective analysis was conducted using longitudinal data from the China Health Statistics Yearbooks. Trends were delineated via descriptive statistics. Equity and spatial evolution were assessed using the Gini coefficient, Theil index decomposition, and spatial autocorrelation analyses (Global Morans I and hotspot analysis). ResultsFrom 2007 to 2023, the total number of pharmacists increased from 357,700 to 569,500 (average annual growth: 2.2%). This growth lagged behind physicians (4.6%) and nurses (7.4%),causing the pharmacist-to-physician ratio to decline from 1:5.15 to 1:8.39. The workforce showed trends of feminization (female proportion rose from 59.7% to 70.8%) and aging. While quality improved, 51.1% still held an associate degree or below, and only 6.6% held senior titles. Equity analysis revealed the provincial Gini coefficient improved from 0.145 to 0.093. Theil index decomposition confirmed intra-provincial disparities as the primary inequality driver. Spatial analysis showed a non-significant global Morans I by 2023 (0.154, P*>0.05), down from 0.254 (P<0.01) in 2007. Hotspot analysis confirmed this transition, revealing a contraction of high-confidence clusters and a trend toward balanced distribution. ConclusionsChina has made measurable progress in expanding pharmacist workforce size and improving inter-provincial equity since 2007. However, persistent structural challenges remain: relative workforce contraction compared to other health professions, an aging demographic, a shortage of senior talent, and significant intra-provincial inequity. Future policies must prioritize optimizing workforce structure and enhancing clinical service capabilities to catalyze a shift toward patient-centered pharmaceutical care. HighlightsO_LIFirst longitudinal study (2002-2023) tracking Chinas institutional pharmacist workforce post-healthcare reform, revealing a critical structural shortage. C_LIO_LIPharmacist growth rate (2.2% annually) severely lagged physicians (4.6%) and nurses (7.4%), causing the pharmacist-to-physician ratio to plummet from 1:5.15 to 1:8.39. C_LIO_LI69.2% of Chinas drug market (prescription drugs) is managed by only 569,500 institutional pharmacists--175,000 fewer than retail pharmacists, exposing a critical workload imbalance. C_LIO_LISpatial disparity paradox: Gini coefficient improved to 0.093 (high equity), yet Theil decomposition revealed intra-provincial (urban/rural) gaps as the primary driver of inequality. C_LIO_LIHigh-level talent deficit: Despite quality gains, only 6.6% hold senior titles and 6.1% have masters degrees--a bottleneck for advancing clinical pharmaceutical care. C_LI

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A policy for delivery of essential medicines to vulnerable population in Argentina: a case study of the REMEDIAR program

Havela, M.; Bartolomeu, L.; Rubinstein, A.

2026-06-08 health systems and quality improvement 10.64898/2026.06.05.26354987 medRxiv
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Essential medicines are one of the cornerstones of financial protection and health equity. The REMEDIAR Program is an initiative of the Argentine Ministry of Health aimed at ensuring free access to essential medicines for the uninsured at the point of care in primary healthcare centers (PHC). This study analyzes the financing, procurement, and distribution of this program over two decades (2002 to 2024). It evaluates how the program's capacity to navigate economic and political challenges ensured an uninterrupted supply of essential drugs at the primary healthcare level in a federal country where health services are devolved to provinces. We adopted a mixed-methods approach to examine the duality between international concessional loans and domestic treasury funding. Findings reveal that while international financing enhanced predictability and efficiency, reducing procurement timelines from 458 to 235 days, it also constrained domestic planning through external conditionalities. Conversely, while national centralized procurement achieved superior price efficiency and lower dispersion, it faced rigidities in adapting to local needs. Territorial distribution analysis confirms that REMEDIAR reduced access barriers for vulnerable households without formal insurance. However, the program entered a stabilization phase, failing to consolidate robust coordination with subnational policies, becoming entrenched in its own operational logic. The study concludes that program effectiveness depends not only on resource volume but on management quality. To guarantee long-term sustainability, transition to national financing requires profound institutional redesign. This must integrate operational capacities with federal coordination and domestic regulations, ensuring that the primary healthcare supply chain remains resilient to macroeconomic volatility and political shifts, aligned with sub-national strategies.

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Systematic Analysis of Housing Referral Outcomes in New York City's WholeYouNYC Social Care Network: Identifying Barriers to Service Connection

Conde, F.

2026-05-22 health systems and quality improvement 10.64898/2026.05.19.26353634 medRxiv
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Background: Health-related social needs (HRSNs), particularly housing instability, are significant drivers of poor health outcomes among Medicaid populations. New York State's Social Care Networks (SCNs) aim to systematically connect members to housing services through coordinated referral systems. However, limited systematic analysis of referral patterns hinders quality improvement efforts. We analyzed housing referral outcomes and workflows to identify barriers to successful service connections. Methods: We conducted a mixed-methods quality improvement study at Public Health Solutions' WholeYouNYC SCN Coordination Center. Quantitative analysis examined 4,258 housing referrals submitted between June 2025 and January 2026, extracted from the Unite Us platform via Power BI dashboard. We calculated acceptance rates, analyzed time metrics, and examined outcomes by receiving organization. Qualitative data were collected through structured consultations with 7 staff members (5 navigators, 2 supervisors) and review of internal workflow documentation. Process mapping identified workflow bottlenecks. Results: Of 4,258 housing referrals, only 45% (n=1,936) were accepted by receiving organizations, while 19% (n=815) were rejected and 32% (n=1,382) remained awaiting response with no recorded action. Average time to acceptance was 8 days for accepted referrals. Acceptance rates were consistent across top receiving organizations (44-46%), suggesting systemic rather than partner-specific barriers. Analysis of unresolved referrals revealed prolonged cases, with the longest pending 271 days. Three critical workflow bottlenecks were identified: CBO response delays, missing housing documentation, and challenges with client engagement. Conclusions: Low housing connection rates (45%) and prolonged unresolved referrals (up to 271 days) indicate systemic barriers requiring interventions at multiple levels. Recommendations include establishing CBO response time benchmarks, implementing automated follow-up protocols, standardizing documentation requirements, and enhancing real-time data monitoring. These findings provide an evidence-based framework for quality improvement in social care coordination programs.

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Development and Internal Validation of a County-Level Screening Index for Postpartum Medicaid Access Barriers

Howard, C.; Shekhar, P.

2026-07-07 health policy 10.64898/2026.07.05.26357332 medRxiv
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Background: Postpartum Medicaid coverage and support are central maternal health policy issues, but county-level tools for identifying where postpartum Medicaid populations may face overlapping administrative, clinical, and contextual access barriers remain limited. Methods: We developed and internally validated a county-level Postpartum Medicaid Access Barrier Index for all 3,144 counties and county equivalents in the 50 states and District of Columbia. Public data sources included geocoded Medicaid office locations from Shafer et al. (2024), U.S. Census county boundaries, American Community Survey 2024 5-year county indicators, the National Center for Health Statistics 2023 Urban-Rural Classification Scheme for Counties, and county-level hospital-based obstetric care status from the University of Minnesota Rural Health Research Center. Medicaid office locations were spatially assigned to counties, then merged with ACS indicators, rurality, and obstetric care status by county FIPS. The theoretical score range was 0-11; the index assigned higher weights to two core infrastructure measures and lower weights to contextual indicators. Internal validation assessed component structure, known-groups validity, geographic clustering, weighting sensitivity, added value over simpler infrastructure screens, and separation across concern levels. Results: Across 3,144 counties, observed scores ranged from 0 to 10 on the theoretical 0-11 score, with a mean of 3.65 and median of 3. High or highest concern counties accounted for 665 counties (21.2%), including 56 counties (1.8%) in the highest concern group. Component correlations were low-to-moderate, with an average absolute phi of 0.176 and no pairwise component correlation at or above 0.50. Known-groups validity was strong: dual administrative and clinical gap counties scored 4.43 points higher than counties with neither gap (Cohen's d = 3.28, p < 0.001). Scores were geographically clustered (Moran's I = 0.375, permutation p = 0.005). A dual-gap-only screen captured 386 of 665 high/highest concern counties (58.0%) but missed 279 high/highest counties; a parsimonious rule requiring one infrastructure gap plus at least four contextual flags recovered 265 of these 279 missed counties (95.0%) with 100.0% precision. Discussion: The Postpartum Medicaid Access Barrier Index provides a transparent county-level screening tool for identifying places where administrative, clinical, and contextual barriers may overlap for postpartum Medicaid populations and should be externally validated against Medicaid enrollment, renewal, churn, coverage continuity, and postpartum care outcomes.

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Accessibility and regional disparities in nationwide 24-hour home medical care: A quantitative evaluation using the enhanced two-step floating catchment area method

Egashira, Y.; Watanabe, R.

2026-04-20 health policy 10.64898/2026.04.18.26351162 medRxiv
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With Japans rapidly aging population, demand for home healthcare is projected to increase by 62% by 2040. This study quantitatively evaluated accessibility to 24-hour home healthcare and regional disparities across all 335 secondary medical areas (SMAs) in Japan using the Enhanced Two-Step Floating Catchment Area (E2SFCA) method. We conducted a nationwide cross-sectional study analyzing approximately 430,000 population points at 500-meter mesh resolution. The E2SFCA integrated demand (age-adjusted population), supply (24-hour home care support clinics and hospitals), and transportation (road networks). Accessibility scores (ASs) and Gini coefficients were calculated for each SMA. Wards hierarchical cluster analysis classified regional types, and multiple regression based on the Penchansky and Thomas five-dimensional access framework identified factors associated with the median AS (ASM) and Gini coefficient. The median ASM was 45.71 (0.00-153.49), and the median Gini coefficient was 0.33 (0.06-0.93). Cluster analysis identified six types ranked by descending ASM, from C1 (high access, equitable; n = 48) to C6 (access desert; n = 23). C6 had a median ASM of 0.00 and Gini coefficient of 0.74, indicating virtually no access within a 30-minute catchment. Home-visit standardized claim ratios, used as external validation, declined monotonically from C1 (125.6) to C6 (17.6). For ASM, 24-hour visiting nursing stations ({beta} = +0.369) and clinic physicians ({beta} = +0.342) showed the strongest positive associations, with non-residential area negatively associated ({beta} = -0.273). For the Gini coefficient, non-residential area showed the strongest positive association ({beta} = +0.523). Taxable income per taxpayer was not significantly associated with either outcome. Non-residential area was associated with both lower accessibility and greater intra-regional inequality, suggesting that geographic constraints may limit the effectiveness of resource investment alone. Uniform nationwide implementation of policies shifting care from long-term care beds to home healthcare may not be feasible; region-specific approaches considering geographic characteristics are necessary.

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Use of the Pharmacy First service in England in the first 12 months: geographic variation and health system context

Meng, W.; Sonnex, K.; Pehlivanli, A.; Allen, T.; Dolan, E.; Glover, R.; Goulding, J.; Higgins, H.; Mays, N.; Taylor, A.; Thornley, T.; Avery, A. J.

2026-06-22 health policy 10.64898/2026.06.18.26355952 medRxiv
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Objectives: The Pharmacy First (PF) service was introduced across England from 31 January 2024 to expand the clinical role of community pharmacies and improve access to primary care. This paper describes use of PF in its first 12 months, in terms of uptake, access routes, consultation outcomes, geographic variations, service costs and antimicrobial supply. Methods: A descriptive analysis of all PF consultations submitted for payment to NHS Business Services Authority in England between 31 January 2024 and 31 January 2025. Pharmacy-level consultation data were linked to national data on population, location and pharmacy characteristics. PF use was examined using population-standardised consultation rates and consultations per pharmacy. Results: During the first year of implementation, 2,205,731 PF consultations were recorded as delivered across 11,349 pharmacies, with payment of GBP123 million to pharmacies. Uptake increased steadily over time. Most consultations were for acute sore throat (33%) and uncomplicated urinary tract infection (27%), with corresponding antibiotics, phenoxymethylpenicillin and nitrofurantoin being the most supplied. Most people self-referred (74%) into the service, with 95% of consultations managed without onward referral. Substantial geographic variation was observed. Northern regions had higher use based on the eligible population. The South East and Midlands had higher activity per pharmacy. London showed a distinct pattern, with higher self-referral into the service, lower medication supply and higher referral to other healthcare services. Higher consultation volume was weakly associated with pharmacy characteristics, including opening hours, pharmacy type and retail setting, and local context, in terms of socio-economic and geographic factors. Conclusions: PF had immediate uptake and is operating primarily as a direct-access model for common acute conditions. Findings suggest that PF is contributing to improved access to care and may shift demand away from general practice. However, the service uptake appears to be shaped by geographic location, proximity to other healthcare services and pharmacy characteristics.

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The Rise of Brazil's Primary Care Digitalization: 12 Billion Records Across 27 Federative Units as a Foundation for Real-World Evidence and Scientific Democratization

Pereira, P. M.; Girotto, A. N.; Silva, G. M.; Duregger, G.

2026-07-04 primary care research 10.64898/2026.07.01.26356080 medRxiv
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Background: Brazil operates one of the world's largest national primary health care information systems. Since 2013, the Health Information System for Primary Care (SISAB), the digital platform of the e-SUS primary care strategy, has collected standardized records of all clinical and community health activities performed by Family Health Strategy teams across all Brazilian municipalities. Yet comprehensive longitudinal analyses of this national data infrastructure remain scarce in the international literature. Methods: Descriptive ecological study with time-series analysis using publicly available secondary data extracted from SISAB on May 18, 2026. Annual records were collected for four production types (Individual Care, Dental Care, Procedures, and Home Visits), disaggregated by all 27 Federative Units, covering April 2013 through March 2026. Per capita indicators were calculated using the 2022 Brazilian Demographic Census population by state. Results: The cumulative total of SISAB records from April 2013 through March 2026 is 12,421,073,299. Annual volume grew from 53.3 million in 2014 (first full year) to 1.96 billion in 2025, an approximately 37-fold increase over 11 years. A 9.0% decline in 2020 was associated with the COVID-19 pandemic, with full recovery by 2021. Procedures rose from 21.6% to 35.9% of total records between 2014 and 2025, reflecting deepening clinical record completeness. Per capita records varied 3.2-fold across federative units, from 29.0 (Distrito Federal) to 92.9 (Tocantins). Home visits, performed predominantly by Community Health Workers, accounted for 41.9% of all records, with the highest per capita rates concentrated in the Northeast region. Conclusions: SISAB constitutes a longitudinal national data infrastructure of exceptional scale, covering populations historically underrepresented in biomedical research: rural, Amazonian, and peri-urban communities. With over 12 years of continuous data and 184 million active registered patients, this system represents a strategic foundation for real-world evidence generation and the democratization of health science. Realizing this potential requires investment in data quality, interoperability, ethical governance, and scientific capacity aligned with Brazilian General Data Protection Law (Law n. 13,709/2018). Keywords: Primary Health Care; Health Information Systems; Family Health Strategy; Digital Health; Brazil; Community Health Workers; Real-World Evidence.

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Effect of NHS surgical hubs on elective primary hip-and-knee replacement volume, length of stay and waiting times: national longitudinal difference-in-differences study

Wen, J.; Anteneh, Z.; Castelli, A.; Street, A.; Gutacker, N.; Scantlebury, A.; Glerum-Brooks, K.; Davies, S.; Bloor, K.; Rangan, A.; Castro Avila, A.; Lampard, P.; Adamson, J.; Sivey, P.

2026-04-22 health policy 10.64898/2026.04.21.26351383 medRxiv
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ObjectivesTo evaluate the effect of surgical hubs on the volume of surgeries, patient waiting times, and length of hospital stay for elective hip and knee replacements in the English NHS. DesignA retrospective longitudinal study using a difference-in-differences approach to compare changes in outcomes at NHS trusts that opened surgical hubs with those that did not. SettingThe study was set in the English NHS, using administrative data from NHS acute trusts providing elective hip and knee replacements between April 2014 and September 2024. ParticipantsThe study included 76 NHS trusts. The treatment group consisted of 29 trusts that opened a surgical hub for trauma and orthopaedic surgery during the study period. The control group consisted of 47 trusts that did not. 48 trusts that performed fewer than 1,000 relevant procedures over the ten-year period or that reported data for fewer than 41 of the 42 quarters in the sample period were excluded. InterventionThe phased introduction of surgical hubs dedicated to elective procedures at 29 NHS trusts between Q1 2020 and Q3 2024. Main outcome measuresThe three main outcomes were, measured at the trust-quarter level: the total number of elective primary hip and knee replacements (surgical volume), the average length of stay in hospital, and the average waiting time from being added to the waiting list to hospital admission. ResultsThe opening of a surgical hub was associated with an increase of 43.75 hip and knee replacement surgeries per quarter (95% CI: 22.22 to 65.28), which represents a 19.1% increase compared to the pre-hub mean. Length of stay was reduced by 0.32 days (95% CI: - 0.48 to -0.16), a 7.8% reduction. There was no statistically significant effect on average waiting times (-14.96 days, 95% CI: -33.11 to 3.19). ConclusionsSurgical hubs appear to be effective at increasing the number of hip and knee replacements and reducing the time patients spend in hospital. However, in this study, they did not lead to a statistically significant reduction in waiting times overall.

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Trends and epidemiological profile of preventable hospitalizations in Honduras (2014 - 2024): An 11-year analysis of ambulatory care sensitive conditions

Alfaro, H. E.; Lara-Arevalo, J.

2026-04-24 health policy 10.64898/2026.04.22.26351522 medRxiv
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Ambulatory Care Sensitive Conditions (ACSCs) are conditions for which effective and timely primary health care (PHC) can prevent hospitalizations. They are widely used as a proxy indicator of access to and quality of PHC. Despite their relevance, evidence from Central America remains scarce. This study aimed to quantify the burden, describe the epidemiological profile, and assess temporal trends of ACSCs hospitalizations in Honduras from 2014 to 2024. We conducted a retrospective observational study using national administrative hospital discharge data from all Ministry of Health hospitals. ACSCs were defined using a standardized list of 20 diagnostic groups based on ICD-10 codes. We estimated percentages and sex-age-standardized hospitalization rates per 10,000 inhabitants. Clinical indicators included length of stay (LOS) and in-hospital fatality rates. Temporal trends were evaluated using joinpoint regression models to estimate annual percent changes (APC). Analyses included stratification by age, sex, and disease category. A total of 4,023,944 hospitalizations were analyzed, of which 547,486 (13.6%) were classified as ACSCs. The overall sex-age-standardized rate was 54.1 per 10,000 inhabitants. ACSCs standardized rates increased between 2014 and 2018 (APC: 2.7%; 95% CI: -2.4; 15.2), declined sharply between 2018 and 2021 (APC: -17.8%; 95% CI: -30.6; -10.3), and increased again between 2021 and 2024 (APC: 15.9%; 95% CI: 4.6; 37.6). Despite this rebound, rates remained below pre-pandemic levels. ACSCs were concentrated among children under 5 years (27.7%) and adults aged 60 years and older (29.9%). Noncommunicable diseases accounted for 56.8% of cases, with diabetes mellitus as the leading cause. Compared with non-ACSCs hospitalizations, ACSCs were associated with longer LOS (4.9 vs. 3.9 days; p <0.001) and higher in-hospital fatality rates (2.4% vs. 1.7%; p <0.001). ACSCs hospitalizations constitute a substantial burden in Honduras and reflect persistent gaps in PHC performance. Strengthening PHC resilience and capacity, particularly for chronic disease management and vulnerable populations, is essential to reduce avoidable hospitalizations and improve health system efficiency and equity.

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Cancer care disruption during the COVID-19 pandemic in Ontario, Canada: A sequential mixed-methods study

Timilshina, N.; Jacobson, D.; Birze, A.; Wodchis, W. P.; Kuluski, K.; Strumpf, E.; Ammi, M.

2026-06-12 health systems and quality improvement 10.64898/2026.06.10.26355360 medRxiv
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Introduction The COVID-19 pandemic profoundly disrupted healthcare delivery worldwide, with cancer care among the most affected services. Prior studies documented delays in referrals, reduced specialist access, and increased provider burden. However, the extent to which these experiences were reflected at the system level remains unclear. Objective To document cancer care experiences and examine whether these experiences were reflected in population-level health system indicators across Ontario, Canada. Methods We used an exploratory sequential mixed-methods design. Qualitative data were collected through focus groups and semi-structured interviews with 32 participants, including patients with cancer (n=8), caregivers (n=5), healthcare providers (n=14), and decision-makers (n=5) across two hospital settings in Ontario, Canada. Emergent themes informed the development of quantitative indicators. We then conducted a retrospective population-based analysis of linked administrative health databases for cancer patients in Ontario (n=87,786) to assess the prevalence of identified themes. Results Four themes emerged: (I) delays in diagnosis and screening; (II) disrupted access to primary care; (III) barriers to specialist and mental health services; and (IV) fragmented care for patients with multimorbidity. Quantitative findings corroborated major themes. Screening rates declined for cervical (64.8% to 57.5%) and breast cancer (64.5% to 57.2%). While in-person primary care shifted almost entirely to virtual modalities (8.5% to 95.4%), overall visit volumes remained stable. Specialist care showed uneven patterns, with increased oncology visits but declines in cardiology and mental health services. Patients with multiple comorbidities experienced the largest reductions in non-oncology specialist care. Conclusion The pandemic disrupted key components of cancer care, particularly screening, access to certain specialist services, and care for patients with complex needs. Integrating qualitative and quantitative evidence highlights areas of system vulnerability and underscores the need for coordinated, resilient cancer care capable of maintaining essential services during future crises.

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A Return-on-Investment Analysis of a Community-Based Diabetes Self-Management Program In New York City

Goldwater, J. C.; Harris, Y.; Das, S. K.; Fernandez Galvis, M. A.; Maru, D.; Jordan, W. B.; Sacaridiz, C.; Norwood, C.; Kim, S. S.; Neustrom, K.

2026-04-23 health economics 10.64898/2026.04.22.26351481 medRxiv
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OBJECTIVETo evaluate the return on investment (ROI) of a community-based Diabetes Self-Management Program (DSMP) enhanced with health-related social needs (HRSN) screening and referrals, implemented by the New York City (NYC) Department of Health and Mental Hygiene with three community-based organizations in highly-impacted, under-resourced neighborhoods. RESEARCH DESIGN AND METHODSA retrospective cost-benefit analysis from a public-sector payer perspective was conducted among 171 adults with type 2 diabetes who completed a six-week, peer-led DSMP delivered by community health workers (CHWs) in English, Spanish, and Korean during 2018-2019. A time-driven, activity-based costing model captured direct implementation costs, CHW workforce turnover, and administrative overhead. Monetized benefits included avoided diabetes-related complications, reductions in self-reported emergency department (ED) visits and hospitalizations, and quality-adjusted life year (QALY) gains from improved medication adherence. Univariate sensitivity analyses tested robustness under conservative assumptions. RESULTSTotal program costs were $179,224; monetized benefits totaled $1,824,213, yielding a net benefit of $1,644,989 and an ROI of 918%--approximately $10 returned per $1 invested. Excluding QALY gains, ROI remained 551%. Self-reported ED visits declined from 149 to 82 and hospitalizations from 93 to 24 in the six months following intervention. Over 80% of participants reported housing instability; 72% were Medicaid-covered and 16% uninsured. Sensitivity analyses confirmed a positive ROI under all conservative scenarios. CONCLUSIONSA CHW-led, community-based DSMP integrated with HRSN screening and referrals delivered substantial economic and public health value among adults facing housing instability and structural barriers to care. Findings support inclusion of DSMP as a covered benefit in Medicaid managed care, value-based payment arrangements, and housing access initiatives to advance equitable diabetes outcomes.

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Creating Equity? A Process Evaluation of Jamkesus Disabilitas, A Disability-Focused Health Financing Scheme in Yogyakarta, Indonesia

Azizatunnisa', L.; Kuper, H.; Probandari, A.; Banks, L. M.

2026-07-01 health systems and quality improvement 10.64898/2026.06.29.26356885 medRxiv
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Background This study aims to explore the initiation and implementation of Jamkesus Disabilitas, a health financing scheme for people with disabilities in Yogyakarta Province, using the UK Medical Research Council (MRC) Process Evaluation for Complex Intervention. Methods We interviewed 19 people with disabilities with different types of impairment as beneficiaries, 3 people from Organisations for People with Disabilities (OPDs), 4 government officials, and 4 health providers, either in person, online, or by phone. Interviews were conducted by LA, and took place in Yogyakarta Province in July-September 2024. Data were analysed using a thematic analysis approach using NVivo 15 software. Findings Jamkesus Disabilitas has improved access to assistive technology (AT) and demonstrated inclusive care through its one-stop service. It also highlights the importance of consistent leadership in disability-inclusive health systems. However, challenges persist, including uneven AT quality, low coverage, limited availability, and inadequate data for evaluation and planning persisted. Moreover, the absence of inclusive features in the regular service means the scheme has not fully closed the equity gap in healthcare access for people with disabilities. Conclusion Jamkesus Disabilitas has expanded access to AT overlooked by the national health insurance (JKN). However, implementation should prioritise AT quality standards, financial and operational sustainability, and stronger data systems. Broader systemic reforms are also needed to embed disability inclusive practices in regular healthcare service delivery. Keywords Health equity, inclusive health system, social protection, health insurance, health financing

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Trends in medication abortion service delivery in the U.S., 2020-2025

Kaller, S.; Schroeder, R.; Berglas, N. F.; Stewart, C.; Upadhyay, U. D.

2026-07-04 sexual and reproductive health 10.64898/2026.07.01.26357048 medRxiv
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Objective: Since 2020, medication abortion provision in the U.S. has been reshaped by changing abortion policies and expanded telehealth access, yet little is known about how medication abortion service delivery has evolved. We examined national trends in service delivery from 2020 to 2025, including changes in abortion facility types, telehealth provision, and gestational limits. Study Design: Using ANSIRHs Abortion Facility Database, a national census of publicly advertising abortion facilities (2020 to 2025), we analyzed trends in medication abortion service delivery. Systematic web searches and mystery shopper calls gathered data on facility types, telehealth provision, and gestational limits. Data analysis included frequencies and comparisons across regions and states. Results: Medication abortion-only facilities increased nationally, from 35% of facilities in 2020 to 65% in 2025, with substantial growth in abortion-restrictive regions such as the Midwest and South. By 2025, 99% of facilities provided medication abortion. Telehealth provision expanded from 7 facilities in 2020 to 606 facilities by 2025, driven by growth in both brick-and-mortar facilities offering telehealth care and new virtual clinics. Overall, 46% of all facilities offered medication abortion by telehealth in 2025. Gestational limits for medication abortion increased nationally, from <1% of facilities offering medication abortion after 11 weeks in 2020 to 38% in 2025. Conclusions: Medication abortion service delivery has adapted to legal and logistical challenges by increasing telehealth options and expanding gestational limits. These changes improve access for abortion seekers, especially those living in restrictive environments. Sustaining abortion access will require ongoing provider adaptation and supportive policy environments.

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Coaching for quality improvement under performance-based contracting: a theory-of-change evaluation in Honduras

Munar, W. J.; Aranda, L. E.; Lauria, M. E.; Bernal Lara, P.; Innocenti, C.; Rodriguez, M.

2026-05-30 health systems and quality improvement 10.64898/2026.05.21.26353487 medRxiv
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Introduction. Practice coaching is increasingly used to strengthen quality improvement (QI) capacity in primary healthcare (PHC) systems in low and middle income countries (LMICs), yet the causal pathways through which it shifts provider behaviour, and the systemic conditions that enable or constrain those pathways, remain under theorised. Using a theory based qualitative evaluation, we examined how and why a practice coaching intervention influenced QI in cervical cancer screening (CCS) and antenatal care (ANC) within Honduras decentralised PHC system during the third phase of the Salud Mesoamerica Initiative (SMI). Methods. We conducted a within case explanatory case study. A programme theory was reconstructed before data collection and iteratively refined against evidence. Data comprised semi structured interviews with 11 midlevel managers, 6 PHC team medical leads, and 2 regional managers, complemented by direct observation and document review. We applied combined deductive and inductive coding, thematic analysis, and pattern matching, and reporting per COREQ. Results. We identified four causal patterns that refined the initial programme theory. Three were activated pathways: (1) novel professional identity among participating managers; (2) collective efficacy and data driven learning, sustained through verifiable progress on observable indicators, strong for CCS but null for ANC, where outcomes were less attributable to teams actions; and (3) relational coordination, psychological safety, and trust, which provided the interpersonal basis for the first two. A fourth, unanticipated pattern showed structural misalignment between coaching enabling, learning based logic and the directive, punitive logic of Honduras performance based contracting environment, confining gains to localised enabling bubbles. Conclusion. Coaching can activate meaningful QI pathways in LMIC primary care, but sustained, equitable impact requires deliberate alignment between coaching learning oriented principles and the institutional performance management architecture, and matching of coaching investment to clinical processes with observable, attributable outcomes.

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Experiences of families using an early example of neighbourhood multidisciplinary care for children and young people: A qualitative exploration using the theoretical framework of acceptability

Litchfield, I.; Dutton, F.; Harper, L.; Kaur, S.; Luxmoore, C.; Rahman, L.; Wolhuter, C.; Bird, C.

2026-05-19 primary care research 10.64898/2026.05.14.26353240 medRxiv
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Background In the United Kingdom, the National Health Service is attempting to address the ongoing challenges to heath equity in underserved children and young people (CYP) by creating Neighbourhood Multi-Disciplinary Teams (NMDTs) that combine health services, social care providers, local authorities, voluntary, community and faith and social enterprise is needed. Despite this significant shift in the delivery of care, there is a lack of suitably robust evidence of family experience to inform their development. This work contributes to this need using the experience and perspectives of families using the experience and perspectives of families using an early example of an NMDT for CYP the Sparkbrook Children's Zone in Birmingham, United Kingdom. Methods The study used data collected from two focus groups conducted with parents whose children had been treated by the Sparkbrook Children's Zone. The data were analysed using a directed content analysis to populate Sekhon's Theoretical Framework of Acceptability. Results In summary and by framework domain, we found that that individuals became aware of the SCZ through a range of sources, understanding that it was multidisciplinary if sometimes unsure of precisely the organisations involved (Intervention coherence) Parents described the benefits to access of a locally situated collocated service (Burden) the personalised relationship with providers (Cultural sensitivity0 extended conultation time, and support for the family's complex clinical needs (Perceived effectiveness) Conclusions Parents appeared to prefer the SCZ over usual primary care but more work is needed with larger sample sizes to ensure that the structure of NMDTs are understood and optimised.

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Hospital staff views on the visibility, role and impact of Acute Learning Disability Liaison Services in Wales: a service evaluation

Sha'aban, A.; Mazzaschi, F. I. M.; Alazizi, A.; McAulay, M.; Edwards, A.; Joseph-Williams, N. I. M.

2026-06-18 health systems and quality improvement 10.64898/2026.06.16.26355793 medRxiv
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People with a learning disability experience marked health inequalities. In Wales, Acute Learning Disability Liaison Services (ALDLS) are delivered by specialised learning disability services, and all roles within them are undertaken by Learning Disability Liaison Nurses (LDLN). These services aim to enable access to, and delivery of, secondary care by supporting reasonable adjustments, facilitating communication, and coordinating care for people with learning disability during hospital encounters. However, independent evidence of the impact of ALDLS on patient care remains limited. This evaluation tries to address this evidence gap by examining hospital staff perceptions of the visibility, role, and impact of ALDLS across Welsh Health Boards, with the aim of informing service design and development and improving secondary care access and care for people with learning disability. The service evaluation used a qualitative approach involving interviews and a focus group with hospital staff across the seven Welsh Health Boards who had experience working with or interacting with ALDLS staff to care for patients with learning disability. Findings cover six key areas including i) visibility and delivery of ALDLS, ii) Barriers and challenges to effective ALDLS delivery, iii) Enablers of effective ALDLS delivery, iv) Positive impacts for patients with learning disability, v) Negative impacts and unintended consequences when the service is absent or limited, and vi) Participants recommendations for future improvements of ALDLS. To synthesise the findings, we developed an overview diagram, which illustrates how ALDLS may influence care quality in acute hospitals. The overview places the liaison service at the centre, showing how organisational enablers and barriers shape its delivery, and how its core functions support improvements in safety, timeliness, effectiveness, efficiency, equity, and patient-centred care. From the findings we have identified recommendations for practice and policy. These include that ALDLS should be recognised as a core, safety-critical component of acute hospital care for people with a learning disability, rather than an optional add-on. In practice, services should be more visibly embedded within routine pathways, with consistent site-based presence, clear referral criteria, early identification through electronic flagging and notification systems, and routine involvement in multidisciplinary planning for complex admissions and procedures. At policy level, ALDLS provision should be recognised within equality and patient safety frameworks as an essential service requiring sustained investment, national minimum configuration standards, adequate staffing, and better-integrated digital systems to support continuity, equitable access, and person-centred care.

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Hospital Price Transparency Data Reveal Up to 8-Fold Geographic Variation in Commercial Rates for IR Procedures

Golshani, P.; Joseph, M. S.

2026-05-13 health economics 10.64898/2026.05.09.26352821 medRxiv
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ObjectiveTo characterize the magnitude and geographic distribution of commercially negotiated hospital facility rates for fourteen common interventional radiology (IR) procedures using publicly posted Hospital Price Transparency Machine-Readable Files (MRFs), and to describe the relationships between state-level commercial pricing, population rurality, and within-system rate uniformity. MethodsIn this cross-sectional observational analysis, we examined hospital-weighted commercial rate observations from U.S. hospital MRFs for fourteen IR procedures spanning image-guided drainage, embolization, peripheral vascular intervention, dialysis access maintenance, and percutaneous spine. The unit of analysis was one observation per distinct negotiated rate per state-CPT cell, deduplicating multi-facility same-system reporting in which two or more hospitals posted identical rate, range, and payer-count tuples. Outliers were excluded using transparent absolute and CMS-relative bounds. State-level statistics were computed where [&ge;]5 distinct hospital-system observations were reported. Commercial rates were compared to CY 2026 CMS Outpatient Prospective Payment System (OPPS) facility payments. Relationships between state-level commercial rate and 2020 U.S. Census percent-rural population were assessed by Spearman rank correlation. ResultsAcross 14 procedures, state-level commercial median rates varied 3.7-to 8.3-fold between the highest- and lowest-priced states. The largest spreads were observed for fem-pop angioplasty (CPT 37224, 8.3-fold), fem-pop atherectomy (37225, 8.1-fold), and iliac stenting (37221, 7.1-fold). National median commercial rates ranged from 1.34x (PAE/GAE) to 3.60x (paracentesis) the corresponding CMS OPPS facility payment. Across all 14 procedures, the relationship between state percent-rural and median commercial rate was negative (mean Spearman {rho} = -0.46, range -0.33 to -0.80; 14 of 14 codes negative), with the most-rural quartile of states showing a median commercial rate 42% below the most-urban quartile. Deduplication identified 660 multi-facility groups in which a single negotiated rate was applied across two or more affiliated hospitals within a state. DiscussionSubstantial state-level variation in commercially negotiated facility rates exists for common IR procedures, with consistently lower rates in more rural states. Within-system rate uniformity is a frequent feature: many regional health systems post identical commercial rates across multiple owned facilities. The findings are consistent with prior literature linking commercial pricing to market structure and support continued investment in price transparency as a precondition for informed decision-making.